Nanomedicine for Drug Delivery and Therapeutics

The book provides a comprehensive in-depth multidisciplinary integration of fundamental concepts and applications of the emerging multifunctional nanomedicines in the areas of medicine, drug delivery, and therapeutics. In the last couple of decades, the development of new biomedical, electronic, and optical tools has provided a unique opportunity to look at materials on a nanoscale. The resultant nanotechnology boom has significantly affected the biological sciences and related areas; imaging at a subcellular level and precise delivery of drugs to tissues are two such important areas. Nanomedicine for Drug Delivery and Therapeutics focuses mainly on the broad areas of research and applications. It presents both a comprehensive overview of the fundamental concepts as well as a practical guide for numerous applications. This exciting new text: Covers the current surgical interventions to treat osteochondral defects, including the nanomaterials developed for osteochondral regeneration Presents the principles of regenerative medicine, the electrospinning process for the production of nanofibers Highlights many anticancer agents, antiviral/bacterial agents, and nucleic acids that are encapsulated in delivery nanotechnology systems Summarizes recent techniques for drug encapsulation, their stimuli-controlled release, passive skin permeation, and transdermal drug administration mechanisms Summarizes the cyclodextrin-based nano-carriers in different areas of drug delivery, particularly for oral, gene, or transdermal deliveries Explores current developments in gene therapy and metal-based therapy with respect to the design of effective drugs for the treatment of HIV infection Discusses applications of organic-inorganic hybrid bio-ceramics Correlates the applications of nanomedicines in diabetes management and nanotechnology Reviews the preparative methods of nano-phosphors, their protein-conjugates, and various physical characterizations to evaluate their possible use in membrane isolation and nano-therapeutics Introduces the potentiometric PVC membrane sensors using different approaches Audience This book is required reading for all those researchers and practitioners who are interested in a comprehensive overview of fundamental concepts and various applications in the multidisciplinary areas of medicine, drug delivery, and therapeutics. As the book covers a wide area of research that integrates biology, chemistry, physics, electronics, sensors, materials science, engineering, and nanotechnology, it also serves as an interdisciplinary guide for post-graduate researchers solving a multitude of research problems.