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Benjamin (Hrsg.) Bonavida

Resistance to Immunotherapeutic Antibodies in Cancer

Strategies to Overcome Resistance

Buch

The current application of antibody-meditated targeted therapy against cancer has resulted in significant objective clinical responses, prolongation of survival and even cures. More than 20 mAbs have been approved for human use targeting a range of different cancers. However, a major drawback of mAb therapeutics is that a subset of patients does not initially respond and another initially responding subset develops resistance to further treatments. At the present time, there are no effective therapies for these subsets of cancer patients. The analyses of underlying mechanisms responsible for resistance are necessary to develop and generate ne… Mehr

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Produktdetails


  • ISBN: 978-1-4614-7653-5
  • EAN: 9781461476535
  • Produktnummer: 14727773
  • Verlag: Springer-Verlag GmbH
  • Sprache: Englisch
  • Erscheinungsjahr: 2013
  • Seitenangabe: 202 S.
  • Masse: H24.1 cm x B16.0 cm x D1.6 cm 494 g
  • Abbildungen: Book; 14 schwarz-weiße und 15 farbige Abbildungen
  • Gewicht: 494

Über den Autor


Dr. Benjamin Bonavida is a professor at UCLA's David Geffen School of Medicine for the Department of Microbiology, Immunology, & Molecular Genetics. His other appointments include being a member of the Department of Defense Congressionally Directed Medical Research Program, Member of the National Cancer Institute's SPORE Program, member of the International Scientific Advisory Board of the Israel Cancer Research Foundation, to name a few. He's currently a scientific reviewer for several journals and a member of editorial boards including Journal of Clinical Immunology, International Journal of Oncology, and Cancer Biotherapy & Radiopharmaceuticals. In his career, he's published over 450 papers and reviews, and he's also edited two books with Springer in the past. For more information, please see the CV attached herewith.

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