Plasminogen-Related Growth Factors
Plasminogen is the inactive precursor of the blood proteinase plasmin, the enzyme responsible for the dissolution of fibrin clots. It has been recognized for several years, however, that plasmin has a broad substrate specificity and can cleave a number of other proteins, including several components of the extracellular matrix. Specific cell surface receptors for the two major plasminogen activators exist on a number of cell types and probably play an important role in controlling plasminogen activation. The identification of plasminogen fragments that lack enzymic activity but affect cell growth and migration, and the discovery of the plasmi…
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Produktdetails
Weitere Autoren: Goode, Jamie A. (Hrsg.)
- ISBN: 978-0-470-51547-1
- EAN: 9780470515471
- Produktnummer: 13949501
- Verlag: Wiley
- Sprache: Englisch
- Erscheinungsjahr: 2008
- Seitenangabe: 268 S.
- Plattform: PDF
- Masse: 18'059 KB
Über den Autor
The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.
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