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Raimund (Reihe Hrsg.) Mannhold

Early Drug Development

Bringing a Preclinical Candidate to the Clinic

Ebook (EPUB Format)

This one-stop reference systematically covers key aspects in early drug development that are directly relevant to the discovery phase and are required for first-in-human studies. Its broad scope brings together critical knowledge from many disciplines, ranging from process technology to pharmacology to intellectual property issues. After introducing the overall early development workflow, the critical steps of early drug development are described in a sequential and enabling order: the availability of the drug substance and that of the drug product, the prediction of pharmacokinetics and -dynamics, as well as that of drug safety. The final s… Mehr

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Produktdetails


Weitere Autoren: Buschmann, Helmut (Reihe Hrsg.) / Holenz, Jörg (Reihe Hrsg.) / Giordanetto, Fabrizio (Hrsg.)
  • ISBN: 978-3-527-80177-0
  • EAN: 9783527801770
  • Produktnummer: 27654013
  • Verlag: Wiley-Vch
  • Sprache: Englisch
  • Erscheinungsjahr: 2018
  • Seitenangabe: 816 S.
  • Plattform: EPUB
  • Masse: 20'368 KB

Über den Autor


Fabrizio Giordanetto graduated in Medicinal Chemistry (Genoa, Italy) followed by his Ph.D. (London, UK) while working for the chemistry unit of Pharmacia - Pfizer (Italy). After positions at AstraZeneca (Sweden) as Principal Scientist and Project Leader and at Taros (Germany) as Head of Medicinal Chemistry, he has recently joined DE Shaw Research LLC (New York, USA) where he leads medicinal chemistry activities and drug discovery projects. During his career, he worked on several drug discovery programs resulting in multiple clinical candidates spanning oncology, CNS, inflammation, metabolic and cardiovascular indications and >100 international patents, peer-reviewed publications and book chapters.

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