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Paul H. Johnson

RNA Interference

Application to Drug Discovery and Challenges to Pharmaceutical Development

Buch

A general overview of RNA interference for the novice readerToday, RNA molecules are used extensively in academic labs and the pharmaceutical industry to probe gene function and validate gene and protein targets for drug discovery. This book provides an overview of RNA interference for those unfamiliar with this rapidly emerging field. It covers mechanisms of action, its applications as a target validation and identification tool, toxicity concerns, and development of siRNA molecules as novel therapeutics.Written by experts in the field, each chapter focuses on an important aspect of RNAi biology or therapeutic discovery and application. Whil… Mehr

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Produktdetails


  • ISBN: 978-0-471-77151-7
  • EAN: 9780471771517
  • Produktnummer: 8260417
  • Verlag: Wiley
  • Sprache: Englisch
  • Erscheinungsjahr: 2011
  • Seitenangabe: 328 S.
  • Masse: H24.2 cm x B16.0 cm x D2.5 cm 697 g
  • Gewicht: 697

Über den Autor


PAUL H. JOHNSON, PhD, is a cofounder and Chief Scientific Officer at PhaseRx, Inc. He is the author of numerous scientific papers and patents, and was the recipient of the 2007 Jeffrey Wenig Memorial Award for Outstanding Achievement in Drug Delivery.

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