Myasthenia Gravis
Disease Mechanism and Immunointervention
Autoimmune myasthenia gravis (MG) is a classical autoimmune disease, for which the target antigen, nicotinic acetylcholine receptor, has been cloned, sequenced and biochemically characterized. Antibodies to acetylcholine receptors destroy acetylcholine receptor at the neuromuscular junction, thus leading to defective neuromuscular transmission, muscle fatigue, and weakness. In the last few years, rapid advances have been made in unraveling the cellular and molecular mechanisms involved in the pathogenesis of MG, both in the animal model, experimental autoimmune MG (EAMG), and in human MG. Significant advances are being made in chara…
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Produktdetails
- ISBN: 978-94-010-5787-5
- EAN: 9789401057875
- Produktnummer: 14714271
- Verlag: Springer Netherlands
- Sprache: Englisch
- Erscheinungsjahr: 2012
- Seitenangabe: 228 S.
- Masse: H23.5 cm x B15.5 cm x D1.2 cm 353 g
- Auflage: Softcover reprint of the original 1st ed. 2000
- Abbildungen: Paperback
- Gewicht: 353
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