Statistical Methods for Survival Trial Design
With Applications to Cancer Clinical Trials Using R
Statistical Methods for Survival Trial Design: With Applications to Cancer Clinical Trials Using R provides a thorough presentation of the principles of designing and monitoring cancer clinical trials in which time-to-event is the primary endpoint. Traditional cancer trial designs with time-to-event endpoints are often limited to the exponential model or proportional hazards model. In practice, however, those model assumptions may not be satisfied for long-term survival trials. This book is the first to cover comprehensively the many newly developed methodologies for survival trial design, including trial design under the Weibull survival mod…
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Produktdetails
- ISBN: 978-0-429-89294-3
- EAN: 9780429892943
- Produktnummer: 31308731
- Verlag: Taylor & Francis Ltd.
- Sprache: Englisch
- Erscheinungsjahr: 2018
- Seitenangabe: 273 S.
- Plattform: PDF
- Masse: 10'076 KB
- Auflage: 1. Auflage
Über den Autor
Jianrong (John) Wu is a professor in the Division of Cancer Biostatistics, Department of Biostatistics, Markey Cancer Center, University of Kentucky. He has more than 15 years' experience of designing and conducting cancer clinical trials at St. Jude Children's Research Hospital and has developed several novel statistical methods for designing phase II and phase III survival trials.
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