Signalling Pathways in Acute Oxygen Sensing
Oxygen sensing is a key physiological function of many tissues, but the identity of the sensor, the signalling pathways linking the sensor to the effector, and the endpoint effector mechanisms are all subjects of controversy. This book evaluates the various mediators that have been proposed, including the mitochondria, NAD(P)H oxidases, cytochrome p450 enzymes, and direct effects on enzymes and ion channels. There has been a resurgence of interest in the role of mitochondria, based partly on the ability of mitochondrial inhibitors to mimic hypoxia, but there is little consensus concerning mechanisms. Some favour the view that the primary sig…
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Produktdetails
Weitere Autoren: Chadwick, Derek J. (Hrsg.)
- ISBN: 978-0-470-03499-6
- EAN: 9780470034996
- Produktnummer: 13955622
- Verlag: Wiley
- Sprache: Englisch
- Erscheinungsjahr: 2006
- Seitenangabe: 300 S.
- Plattform: PDF
- Masse: 3'252 KB
Über den Autor
The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.
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