Markus (Hrsg.) Müller

Microdialysis in Drug Development

Ebook (PDF Format)

In vivo target site concentrations are probably the most important determinant of drug effects. Traditionally, linking drug concentrations to drug effects has been accomplished by modelling blood-derived data, mostly because a direct quantification of tissue concentrations has been beyond technical reach. Today, a direct measurement of target site concentrations is possible by employing microdialysis or complementary approaches such as imaging technologies. Microdialysis, initially conceived in the 1970ies, has become a standard tool in drug development. This comprehensive overview of current microdialysis technology covers general and diseas… Mehr

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Produktdetails

ISBN: 978-1-4614-4815-0
EAN: 9781461448150
Produktnummer: 18250815
Verlag: Springer
Sprache: Englisch
Erscheinungsjahr: 2012
Seitenangabe: 338 S.
Plattform: PDF
Masse: 5'019 KB

Über den Autor

Prof. Markus Müller, MD is Head of the Department of Clinical Pharmacology at the Medical University of Vienna in Austria. He is specialized in Internal Medicine and Clinical Pharmacology and is an international expert in clinical research. He has published over 80 articles on the use and methodology of microdialysis in clinical drug development.