Crossroads between Innate and Adaptive Immunity

This compilation presents minireviews derived from work presented at the Aegean Conference: First Crossroads between Innate and Adaptive Immunity, which occurred October 9-14, 2005 at the Hilton Conference Center on the island of Rhodes, Greece. The conference included sessions dedicated to host recognition of and response to pathogens, innate immune networks, antigen presentation, and adaptive immune responses, each headlined by a leading scientist at the forefront of that field. The intimate networking and interaction of dendritic cells, T cells, B cells, NK cells, NK-T cells, and complement during the host response to pathogens and tumors are only now starting to be elucidated. The respective fields that focus on these immune cells and molecules tend to exist in parallel worlds, with minimum exchange of information and ideas. The goal of this conference was to initiate crosstalk between these immunological fields, and to promote and facilitate discussion on the interactions between the innate immune response and the adaptive immune response, and ultimately breed collaboration between these areas of study. TOC:Signal Transduction In Dc Differentiation.- Shaping Naïve And Memory Cd8+ T Cell Responses In Pathogen Infections Through Antigen Presentation.- Understanding The Role Of Innate Immunity In The Mechanism Of Action Of The Live Attenuated Yellow Fever Vaccine-17d.- The Function Of Local Lymphoid Tissues In Pulmonary Immune Responses.- The Yin And Yang Of Adaptive Immunity In Allogeneic Hematopoietic Cell Transplantation: Donor Antigen-Presenting Cells Can Either Augment Or Inhibit Donor T-Cell Allo-Reactivity.- It's Only Innate Immunity But I Like It.- Innate Tumor Immune Surveillance.- Regulation Of Adaptive Immunity By Cells Of The Innate Immune System: Bone Marrow Natural Killer Cells Inhibit T Cell Proliferation .- Induction And Maintenance Of Cd8+ T Cells Specific For Persistent Viruses.- Germinal Center-Derived B Cell Memory.- Cd28 And Cd27 Costimulation Of Cd8+ T Cells:A Story Of Survival.- Cd38: An Ecto-Enzyme At The Crossroads Of Innate And Adaptive Immune Responses.- Vascular Leukocytes: A Population With Angiogenic And ImmunossuppressiveProperties Highly Represented In Ovarian Cancer.- Cd4+ T Cells Cooperate With Macrophages For Specific Elimination Of Mhc ClassIi-Negative Cancer Cells.- Receptors And Pathways In Innate Antifungal Immunity.