Uwe (Hrsg.) Gottschalk

Process Scale Purification of Antibodies

Ebook (PDF Format)

Traditional column chromatography dominates current purification technology, and many of the productivity gains that have been achieved have relied on upscaling such devices. However, this comes with a cost penalty and the pharmaceutical industry has reached the point at which further upscaling becomes economically unsupportable. This book offers a broad-based reassessment of old and new purification methods, incorporating an analysis of innovative new trends in purification. The book has wide coverage of different antibody purification strategies and brings together top-tier experts to address problems in process-scale antibody purification. Mehr

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Produktdetails

ISBN: 978-0-470-44488-7
EAN: 9780470444887
Produktnummer: 13931918
Verlag: John Wiley & Sons
Sprache: Englisch
Erscheinungsjahr: 2009
Seitenangabe: 456 S.
Plattform: PDF
Masse: 3'497 KB
Auflage: 1. Auflage

Über den Autor

Uwe Gottschalk, PhD, is Group Vice President, Purification Technologies, at Sartorius Stedim Biotech. Previously, he worked for Bayer Health Care, overseeing the purification of monoclonal antibodies and recombinant proteins produced in various expression systems. Dr. Gottschalk received a doctorate in chemistry from the University of Münster. He lectures at the University of Duisburg-Essen and the EPFL in Lausanne, Switzerland and has written extensively in the areas of biotechnology and somatic gene therapy.