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Marcus (Hrsg.) Hompesch

Translational Research Methods for Diabetes, Obesity and Cardiometabolic Drug Development

A Focus on Early Phase Clinical Studies

Ebook (PDF Format)

This book aims to aid the selection of the most appropriate techniques for use in early phase (1 and 2) clinical studies of new drugs for diabetes, obesity, and related cardiometabolic disease.Clinical research methods for assessing the pharmacokinetics and pharmacodynamics of new diabetes drugs, e.g. the euglycaemic clamp technique, have become well-established in proof-of-mechanism studies; however, selection of the best techniques is by no means straightforward.This book will aid the understanding of the need for new pharmacotherapies for type 1 diabetes, type 2 diabetes, and obesity and the molecular targets of drugs currently in developm… Mehr

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Produktdetails


Weitere Autoren: Heinemann, Lutz (Hrsg.) / Krentz, Andrew J. (Hrsg.)
  • ISBN: 978-1-4471-4920-0
  • EAN: 9781447149200
  • Produktnummer: 17328953
  • Verlag: Springer
  • Sprache: Englisch
  • Erscheinungsjahr: 2014
  • Plattform: PDF
  • Masse: 8'418 KB

Über den Autor


Andrew J Krentz, Senior Director of Scientific Services at the Profil Institute, is a clinical academic with more than three decades of experience in diabetes and cardiometabolic medicine. He holds a visiting chair at the Bedfordshire & Hertfordshire Postgraduate Medical School, University of Bedfordshire UK where he was Associate Professor before joining Profil. Prior to this he was a senior physician in internal medicine, diabetes & endocrinology at Southampton University Hospitals, UK. Lutz Heinemann, Senior Scientific Consultant at the Profil Institute, has acted as scientific advisor for Profil Institute since the company's inception in 2004. He consults on the design of clinical trial protocols and in the publication of study results. He is also co-founder of Profil Institute for Metabolic Research in Neuss, Germany and led the company as CEO for 10 years until 2009. Prior to that, Prof. Dr. Heinemann spent 17 years performing diabetes-related clinical and experimental research at the Department of Metabolic Diseases and Nutrition, a World Health Organization Collaborating Center of Diabetes, at Heinrich-Heine University of Düsseldorf in Germany. Marcus Hompesch, President and Chief Executive Officer, Profil Institute, is an expert in the field of metabolic diseases, a licensed physician and entrepreneur. His experience in designing, performing and publishing clinical studies in metabolic diseases has been gained through over 18 years of work as clinician and clinical researcher. Dr. Hompesch established Profil Institute for Clinical Research in San Diego, CA in 2003.

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