Connexin Cell Communication Channels

Ernesto Oviedo-Orta received his MD from the Havana Medical School in Cuba where he also specialized in clinical immunology. During his postgraduate specialist training, he engaged in vaccine research related to diverse infectious agents and diseases, including measles and hepatitis C. Dr. Oviedo-Orta's Ph.D. research work in Cardiff, UK, focused on the role of gap junction intercellular communication in the immune system. His work continued in this area both in Bristol and Guildford, UK, but with special attention to immune regulation. Dr. Oviedo-Orta is currently a Clinical Sciences Expert at Novartis Vaccines & Diagnostics, Siena, Italy, where he is a medical and scientific advisor supporting new and ongoing projects in vaccine research and clinical development.Brenda R. Kwak studied at the University of Amsterdam, the Netherlands, where she also obtained her PhD. Dr. Kwak carried out her PhD research work focusing on the regulation of cardiac gap junction channels using a dual patch-clamp approach. She then continued her work for several years as a postdoctoral fellow at the University of Utrecht, the Netherlands. After moving to the University of Geneva, she focused on the vascular system, first in the endothelium at the Department of Morphology, and later on the regulation of major histocompatibility complex class II (MHC-II) in the context of atherosclerosis at the Department of Internal Medicine-Cardiology. On receiving a professorship from the Swiss National Science Foundation in 2003, she established an independent research group in the same department to dissect the role of Cxs in atherosclerosis. She is now associate professor to both the Department of Pathology and Immunology and to the Department of Internal Medicine-Cardiology at the University of Geneva and focuses more broadly on the role of Cxs in cardiovascular physiology and pathology, work that still includes atherosclerotic disease but