DNA Repair, Genetic Instability, and Cancer
This volume describes the elaborate surveillance systems and various DNA repair mechanisms that ensure accurate passage of genetic information onto daughter cells. In particular, it narrates how the cell cycle checkpoint and DNA repair machineries detect and restore DNA damages that are embedded in millions to billions of normal base pairs. The scope of the book ranges from biochemical analyses and structural details of DNA repair proteins, to integrative genomics and population-based studies. It provides a snapshot of current understanding about some of the major DNA repair pathways, including base-excision repair, nucleotide excision repair…
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Produktdetails
Weitere Autoren: Li, Lei (Hrsg.) / Chen, David J. (Hrsg.)
- ISBN: 978-981-270-014-8
- EAN: 9789812700148
- Produktnummer: 2827861
- Verlag: World Scientific Pub Co Inc
- Sprache: Englisch
- Erscheinungsjahr: 2007
- Seitenangabe: 376 S.
- Masse: H23.9 cm x B15.9 cm x D2.4 cm 713 g
- Gewicht: 713
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