Biology of IGF-1
Its Interaction with Insulin in Health and Malignant States
Insulin-like growth factor (IGF-1) is an anabolic effector hormone that, in recent years, has been linked with several types of malignancy. These include prostate, ovarian and colon cancers. However, the nature of this relationship with cancer is uncertain and the linkage itself is controversial. The IGF-1 receptors and signalling pathways are similar to those of insulin, even though the biological actions of these hormones are different. Because of the similarities, insulin is often also considered when the link between IGF-1 and cancer is discussed. The clinical use of long-term growth hormone treatment is increasing and such treatment lead…
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Produktdetails
Weitere Autoren: Goode, Jamie A. (Hrsg.)
- ISBN: 978-0-470-86999-4
- EAN: 9780470869994
- Produktnummer: 13819026
- Verlag: Wiley
- Sprache: Englisch
- Erscheinungsjahr: 2005
- Seitenangabe: 288 S.
- Plattform: PDF
- Masse: 4'190 KB
Über den Autor
The Novartis Foundation is an international scientific and educational charity which promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.
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