Crack in Creation

BY THE WINNER OF THE 2020 NOBEL PRIZE IN CHEMISTRY Finalist for the Los Angeles Times Book Prize ';The future is in our hands as never before, and this book explains the stakes like no other.' George Lucas';Required reading for every concerned citizen.' New York Review of Books Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. That is, until 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the gene-editing tool CRISPRa revolutionary new technology that she helped createto make heritable changes in human embryos. The cheapest, simplest, most effective way of manipulating DNA ever known, CRISPR may well give us the cure to HIV, genetic diseases, and some cancers. Yet even the tiniest changes to DNA could have myriad, unforeseeable consequences, to say nothing of the ethical and societal repercussions of intentionally mutating embryos to create ';better' humans. Writing with fellow researcher Sam Sternberg, Doudnawho has since won the Nobel Prize for her CRISPR researchshares the thrilling story of her discovery and describes the enormous responsibility that comes with the power to rewrite the code of life. ';An invaluable account . . . We owe Doudna several times over.' Guardian