Drugs as Tools in Neurotransmitter Research
Serendipitous discovery has played an important role m the identification of physiological mechanisms in central and peri- eral neurotransmission. In many cases, the subsequent followup of these discoveries has been substantially aided by previouslyiden- fied natural substances that interfered with these mechanisms. The site of neuromuscular blockade produced by curare extracts, for example, was shown in the 1850s by Claude Bernard, and Sir Henry H. Dale m 1906 discovered the reversal of the pressor effects of adrenal extracts by ergot alkaloids. These findings were the first clues that led eventually to the definition of mcotinic cholinergic…
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Produktdetails
Weitere Autoren: Boulton, Alan A. (Hrsg.) / Juorio, Augusto V. (Hrsg.)
- ISBN: 978-1-4899-4105-3
- EAN: 9781489941053
- Produktnummer: 16766190
- Verlag: Humana Press
- Sprache: Englisch
- Erscheinungsjahr: 2013
- Seitenangabe: 532 S.
- Masse: H22.9 cm x B15.2 cm x D2.8 cm 762 g
- Auflage: Softcover reprint of the original 1st ed. 1989
- Abbildungen: Paperback
- Gewicht: 762
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