Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles
Application to Drug Delivery System
Recent advances witness the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites.To optimize and then enhance the efficacy and specificity, the control and guidance of drug carriers in vasculature has become crucial. Current bottlenecks in the optimal design of drug carrying particles are the lack of knowledge about the transport of particles, adhesion on endothelium wall and subsequent internalization into diseased cells. To study the transport and adhesion of particle in vasculature, the authors have made great efforts to numerically investigate the dynamic and adhesive motions of p…
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Produktdetails
Weitere Autoren: Shen, Zhiqiang / Li, Ying
- ISBN: 978-1-64327-791-2
- EAN: 9781643277912
- Produktnummer: 33383191
- Verlag: Morgan & Claypool Publishers
- Sprache: Englisch
- Erscheinungsjahr: 2020
- Seitenangabe: 111 S.
- Plattform: EPUB
- Masse: 8'497 KB
Über den Autor
Huilin Ye is a PhD candidate in Mechanical Engineering at University of Connecticut. His research interest is mainly of developing high-fidelity computational methods in biosystem, especially for the blood flow. The novel numerical scheme has been successfully applied in the targeted drug delivery system for capturing the dynamic motion of micro- and nano-particles in blood flow. Ye's works have been recognized by fellowships and awards including Generic Electric Fellowship for Innovation and Best paper award of FDTC Student paper competition in EMI(2018) from ASCE.
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