Drug Disposition and Pharmacokinetics

Drug Disposition and Pharmacokinetics, is an authoritative, comprehensive book on the fate of drug molecules in the body, including implications for pharmacological and clinical effects. This book provides a unique, balanced approach, examining the specific physical and biological factors affecting the absorption, distribution, metabolism and excretion of drugs, together with mathematical assessment of the concentrations in plasma and body fluids. Understanding the equations requires little more than a basic knowledge of algebra, laws of indices and logarithms, and very simple calculus. A vigorous, balanced account of the processes underlying drug disposition and the practical uses of pharmacokinetic derivations. Generously illustrated with examples, tables and figures. Written by two experienced authors with a proven track record in research, teaching and industry. A companion website contains additional equations and examples: www.wiley.com/go/currydrug Whilst this book has its roots in the highly acclaimed book of the same name, written by Stephen Curry nearly thirty years ago, it is essentially a new book having been restructured and largely rewritten. This readable and informative book will prove invaluable to professionals and students needing to develop a rational approach to the investigation and application of drugs.