Proteopathic Seeds and Neurodegenerative Diseases
The misfolding and aggregation of specific proteins is an early and obligatory event in many of the age-related neurodegenerative diseases of humans, and appears to occur many years before the onset of clinical symptoms. The initial cause of this pathogenic cascade and the means whereby disease spreads through the nervous system, remain uncertain. A recent surge of research, first instigated by pathologic similarities between prion disease and Alzheimer's disease, has increasingly implicated corruptive protein templating, or seeding, as a prime factor in the neurodegenerative process. The prion-like corruption of proteins also characterizes s…
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Produktdetails
Weitere Autoren: Jucker, Mathias (Hrsg.)
- ISBN: 978-3-642-44696-2
- EAN: 9783642446962
- Produktnummer: 17557432
- Verlag: Springer Berlin Heidelberg
- Sprache: Englisch
- Erscheinungsjahr: 2015
- Seitenangabe: 168 S.
- Masse: H23.5 cm x B15.5 cm x D0.9 cm 265 g
- Auflage: 2013
- Abbildungen: Paperback
- Gewicht: 265
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