The Organometallic Chemistry of the Transition Metals

Each edition of this organometallics book . . . keeps getting better . . . useful as a reference . . . useful for undergraduate and graduate students. -Choice on the Thir d Edition There have been a number of notable advances in the field of organometallic chemistry over the past decade. Transition metal organometallic chemistry has provided researchers- especially those working in the pharmaceuticals, natural product synthesis, and polymer industries-with powerful new synthetic tools, and the field has expanded to include life science aspects, such as metalloenzymes involving organometallic intermediates and nanotechnology, such as nanoparticles and giant molecules. Fully updated and expanded to reflect recent advances, this Fourth Edition of the classic text provides students and professional chemists with a comprehensive introduction to the principles and general properties of organometallic compounds. It also supplies a wealth of practical information about relevant reaction mechanisms, along with detailed descriptions of contemporary applications to organic synthesis, organized by reaction type. Additionally, the numerous references to pertinent literature found throughout the text are appreciated by students and professional chemists alike. New to this edition are: A new section on elements of the f-block and expanded coverage of paramagnetic organometallic compounds. Extensively revisions to the chapter on organic synthetic applications including new sections on coupling, metathesis, nucleophilic substitution, Lewis acid reactions, chiral bases and other catalytic reactions Significant updates to the chapter on bioorganometallic chemistry, including hydrogenase, acetyl CoA synthase, and methyl CoM reductase, as well as a discussion of biomedical applications. Bibiliographic references to many useful reviews The Organometallic Chemistry of the Transition Metals, Fourth Edition is an unparalleled pedagogic resource, appropriate as a main text for courses in inorganic chemistry and organometallic chemistry, and as a supplementary text for courses in bioinorganic chemistry. It is also a valuable working reference for professional chemists who need to become better acquainted with the subject.