Günter Mayer
The Chemical Biology of Nucleic Acids
Ebook (PDF Format)
This book focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guid…
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Beschreibung
This book focuses on the methods for obtaining modified and native nucleic acids, and their biological applications. Topics covered include: chemical synthesis of modified RNA expansion of the genetic alphabet in nucleic acids by creating new base pairs chemical biology of DNA replication: probing DNA polymerase selectivity mechanisms with modified nucleotides nucleic-acid-templated chemistry chemical biology of peptide nucleic acids (PNA) the interactions of small molecules with DNA and RNA the architectural modules of folded RNAs genesis and biological applications of locked nucleic acid (LNA) small non-coding RNA in bacteria microRNA-guided gene silencing nucleic acids based therapies innate immune recognition of nucleic acid light-responsive nucleic acids for the spatiotemporal control of biological processes DNA methylation frameworks for programming RNA devices RNA as a catalyst: The Diels-Alderase-Ribozyme evolving an understanding of RNA function by in vitro approaches the chemical biology of aptamers: synthesis and applications nucleic acids as detection tools bacterial riboswitch discovery and analysis A comprehensive reference for bioorganic chemists, chemical biologists, medicinal chemists, cell biologists, and molecular biologists.
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Produktdetails
- ISBN: 978-0-470-66401-8
- EAN: 9780470664018
- Produktnummer: 13911262
- Verlag: Wiley
- Sprache: Englisch
- Erscheinungsjahr: 2010
- Seitenangabe: 478 S.
- Plattform: PDF
- Masse: 13'610 KB
Über den Autor
Günter Mayer, Assistant Professor, LIMES Prog. Unit Chemical Biology and Medicinal Chemistry, Kekulé-Institute for Organic Chemistry and Biochemistry, University of Bonn, GermanyProfessor Mayer's research involves molecular diversity applied to elucidate the conformation, function and identity of biomolecules. He is a co-founder of NascaCell Technologies AG, a leading service provider of innovative biomolecules, where he headed the combinatorial biotechnology department. He has published papers in leading journals such as Nature, Angewandte Chemie and Journal of the American Chemical Society.
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