Assessing Rare Variation in Complex Traits
Design and Analysis of Genetic Studies
This unique volume is the first to cover a wide range of design and analysis issues in genetic studies of rare variants, with contributions from experts in the field, through large-scale international consortia including the UK10K Project, GO-T2D and T2D-GENES. The book presents state-of-the-art methodology for rare variant detection and calling, imputation, and analysis in samples of unrelated individuals and families. It also covers analytical issues associated with the study of rare variants, such as the impact of fine-scale population structure, and rare variants studies in a meta-analysis framework. This book covers multiple aspects of s…
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Produktdetails
Weitere Autoren: Morris, Andrew (Hrsg.)
- ISBN: 978-1-4939-2824-8
- EAN: 9781493928248
- Produktnummer: 18905660
- Verlag: Springer-Verlag GmbH
- Sprache: Englisch
- Erscheinungsjahr: 2015
- Seitenangabe: 263 S.
- Plattform: PDF
- Masse: 6'820 KB
- Auflage: 1st ed. 2015
- Abbildungen: 10 schwarz-weiße und 26 farbige Abbildungen, 14 schwarz-weiße Tabellen, Bibliographie
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