Medicinal Chemistry of Nucleic Acids

Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biologyAssembling contributions from a collection of authors with expertise in all areas of nucleic acids, medicinal chemistry, and therapeutic applications, Medicinal Chemistry of Nucleic Acids presents a thorough overview of nucleic acid chemistry--a rapidly evolving and highly challenging discipline directly responsible for the development of antiviral and antitumor drugs. This reliable resource delves into a multitude of subject areas involving the study of nucleic acids--such as the new advances in genome sequencing, and the processes for creating RNA interference (RNAi) based drugs--to assist pharmaceutical researchers in removing roadblocks that hinder their ability to predict drug efficacy. Offering the latest cutting-edge science in this growing field, Medicinal Chemistry of Nucleic Acids includes:* In-depth coverage of the development and application of modified nucleosides and nucleotides in medicinal chemistry* A close look at a large range of current topics on nucleic acid chemistry and biology* Essential information on the use of nucleic acid drugs to treat diseases like cancer* A thorough exploration of siRNA for RNAi and the regulation of microRNA, non-coding RNA (ncRNA), a newly developing and exciting research areaThorough in its approach and promising in its message, Medicinal Chemistry of Nucleic Acids probes the new domains of pharmaceutical research--and exposes readers to a wealth of new drug discovery opportunities emerging in the dynamic field of nucleic acid chemistry.