Chirality in Drug Research
Most pharmaceutically active compounds possess a chirality that greatly influences their pharmacological properties. Since all pharmaceutical products nowadays are produced in chirally pure form, this places huge demands on the technology used for drug synthesis, purification, analysis and testing. Here, the two editors from academia and a major pharmaceutical company have assembled an experienced, international team to provide first-hand practical advice and report previously unpublished data. Divided into the three main sections of synthesis, analysis and drug development, this handbook covers all stages of the drug development process, inc…
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Produktdetails
Weitere Autoren: Folkers, Gerd (Reihe Hrsg.) / Kubinyi, Hugo (Reihe Hrsg.) / Francotte, Eric (Hrsg.) / Lindner, Wolfgang (Hrsg.)
- ISBN: 978-3-527-60871-3
- EAN: 9783527608713
- Produktnummer: 13870744
- Verlag: Wiley-Vch
- Sprache: Englisch
- Erscheinungsjahr: 2007
- Seitenangabe: 370 S.
- Plattform: PDF
- Masse: 6'099 KB
Über den Autor
Eric Francotte received his BS and PhD degrees from the University of Louvain (Belgium). After postdoctoral work at the University of Geneva, he joined the Central Research Laboratories at Ciba-Geigy, where he was working on optically active polymers. He is now Director and Head of Separations at the Novartis Institutes for BioMedical Research in Basel (Switzerland). He is also an editor of the Wiley journal Chirality. His major interests include development and applications of chiral stationary phases for the separation of stereoisomers on an analytical and preparative scale. Wolfgang Lindner received his PhD degree in Organic Chemistry from the University of Graz (Austria). After several academic positions, including a period at the FDA in Bethesda (USA), he was appointed the chair in Analytical Chemistry at the University of Vienna (Austria). He is also the editor of the Journal of Chromatography B, and the current president of the Austrian Society of Analytical Chemistry. His major interests lie in enantioselective separation techniques, including LC, CE, membranes, extractions, and in stereoselective pharmacokinetics.
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