Drug Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
21 Kapitel, durchgesehen und aktualisiert: In diesem neu aufgelegten Standardwerk erklären Wirkstoffforscher aus dem akademischen und industriellen Umfeld alle Faktoren, die die Bioverfügbarkeit von Wirkstoffen beeinflussen. Teil 1 konzentriert sich auf die Messung physikalischer Eigenschaften (in vivo und in vitro), Teil 2 diskutiert Löslichkeit und gastrointestinale Absorption, Teil 3 widmet sich Fragen des Metabolismus und der Exkretion. Der besonders intensiv überarbeitete Teil 4 geht auf moderne Computermodelle zur Abschätzung der Bioverfügbarkeit potenzieller Wirksubstanzen ein. Der letzte Teil beschäftigt sich mit der Verbesserung der…
Mehr
CHF 215.00
Preise inkl. MwSt. und Versandkosten (Portofrei ab CHF 40.00)
Versandkostenfrei
Produktdetails
Weitere Autoren: Folkers, Gerd (Reihe Hrsg.) / Kubinyi, Hugo (Reihe Hrsg.) / Waterbeemd, Han van de (Hrsg.) / Testa, Bernard (Hrsg.)
- ISBN: 978-3-527-62387-7
- EAN: 9783527623877
- Produktnummer: 13888678
- Verlag: Wiley-Vch
- Sprache: Englisch
- Erscheinungsjahr: 2009
- Seitenangabe: 649 S.
- Plattform: PDF
- Masse: 6'221 KB
- Auflage: 2. Aufl.
Über den Autor
Han van de Waterbeemd studied physical organic chemistry at the Technical University of Eindhoven, and gained his PhD in medicinal chemistry from the University of Leiden. After an academic career at the University of Lausanne with Bernard Testa, he worked for 20 years in the pharmaceutical industry for Roche, Pfizer and AstraZeneca. His research interests are in optimizing compound quality using measured and predicted physicochemical and DMPK properties. He has contributed to 145 research papers and book chapters, and (co-)edited 13 books, and was involved in organizing conferences and courses to promote medicinal chemistry, with a focus on physicochemistry and predictive approaches in drug design. Dr. van de Waterbeemd is on the editorial board of several journals and of Methods and Principles in Medicinal Chemistry. Bernard Testa is Emeritus Professor of the University of Lausanne, having served there for 25 years as a full professor and head of medicinal chemistry. He has written 5 books and edited 33 others, and (co)-authored well over 450 research and review articles in the fields of drug design and drug metabolism. Between 1994 and 1998, he was the European Editor of Pharmaceutical Research, and is now a senior editor of Chemistry and Biodiversity, as well as serving on the editorial boards of several leading journals. Professor Testa holds honorary doctorates from the universities of Milan, Montpellier and Parma, and is a recipient of the Nauta Award on Pharmacochemistry given by the European Federation for Medicinal Chemistry.
100 weitere Werke von Raimund (Reihe Hrsg.) Mannhold:
Chemoinformatics in Drug Discovery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 242.00
Protein Crystallography in Drug Discovery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 170.00
Aspartic Acid Proteases as Therapeutic Targets
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 186.00
Protein Kinases as Drug Targets
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 156.00
G Protein-Coupled Receptors as Drug Targets
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 215.00
Proteomics in Drug Research
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 209.00
Molecular Descriptors for Chemoinformatics
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 425.00
Transporters as Drug Carriers
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 193.00
Chemogenomics in Drug Discovery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 220.00
Molecular Modeling
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 153.00
Evolutionary Algorithms in Molecular Design
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 164.00
Virtual Screening
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 170.00
Data Mining in Drug Discovery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 153.00
Scaffold Hopping in Medicinal Chemistry
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 153.00
Phosphodiesterases and Their Inhibitors
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 131.00
Ligand Design for G Protein-coupled Receptors
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 200.00
Protein-Ligand Interactions
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 156.00
Microwaves in Organic and Medicinal Chemistry
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 198.00
Combinatorial Chemistry
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 182.00
Chemokine Receptors as Drug Targets
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 159.00
Protein-Ligand Interactions
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 156.00
Protein-Protein Interactions in Drug Discovery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 156.00
Drug Metabolism Prediction
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 164.00
Drug Selectivity
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 441.00
Drug Selectivity
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 441.00
Epigenetic Drug Discovery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 175.00
Epigenetic Drug Discovery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 195.00
Innovative Dosage Forms
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 195.00
Neglected Tropical Diseases
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 195.00
Target Discovery and Validation
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 175.00
Innovative Dosage Forms
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 195.00
Drug Metabolism Prediction
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 164.00
New Drug Development for Known and Emerging Viruses
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 429.00
Microwaves in Organic and Medicinal Chemistry
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 198.00
Pharmacophores and Pharmacophore Searches
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 193.00
Protein-Ligand Interactions
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 153.00
Fragment-based Approaches in Drug Discovery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 220.00
Pharmacokinetics and Metabolism in Drug Design
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 122.00
Bioisosteres in Medicinal Chemistry
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 137.00
Natural Products in Medicinal Chemistry
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 175.00
Bioisosteres in Medicinal Chemistry
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 137.00
Predictive Toxicology
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 153.00
Predictive Toxicology
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 153.00
Protein-Protein Interactions in Drug Discovery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 156.00
Phosphodiesterases and Their Inhibitors
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 131.00
In vivo Models for Drug Discovery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 164.00
Protein Therapeutics, 2 Volume Set
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 175.00
Protein Therapeutics, 2 Volume Set
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 175.00
Transporters as Drug Targets
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 164.00
Transporters as Drug Targets
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 164.00
Early Drug Development
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 308.00
Early Drug Development
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 308.00
Neglected Tropical Diseases
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 195.00
Fragment-based Drug Discovery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 164.00
Reactive Drug Metabolites
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 156.00
Quantum Medicinal Chemistry
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 170.00
Drug Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 148.00
Virtual Screening
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 170.00
Molecular Biology in Medicinal Chemistry
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 198.00
Antiviral Drug Strategies
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 159.00
Mass Spectrometry in Medicinal Chemistry
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 215.00
Lead Generation
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 164.00
Lead Generation
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 164.00
Molecular Interaction Fields
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 198.00
Prodrugs and Targeted Delivery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 164.00
Virtual Screening for Bioactive Molecules
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 164.00
Structure-based Ligand Design
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 153.00
Lipophilicity in Drug Action and Toxicology
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 127.00
Antitargets
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 182.00
Aspartic Acid Proteases as Therapeutic Targets
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 186.00
Prodrugs and Targeted Delivery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 164.00
Nuclear Receptors as Drug Targets
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 215.00
Pharmacokinetics and Metabolism in Drug Design
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 137.00
Reactive Drug Metabolites
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 156.00
Data Mining in Drug Discovery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 153.00
Natural Products in Medicinal Chemistry
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 175.00
Scaffold Hopping in Medicinal Chemistry
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 153.00
Voltage-Gated Ion Channels as Drug Targets
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 215.00
Chemokine Receptors as Drug Targets
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 159.00
Combinatorial Chemistry
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 253.00
Chemometric Methods in Molecular Design
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 153.00
High-Throughput Screening in Drug Discovery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 198.00
Qsar
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 140.00
Handbook of Molecular Descriptors
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 314.00
Drug-Membrane Interactions
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 142.00
In vivo Models for Drug Discovery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 164.00
Target Discovery and Validation
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 175.00
Thermodynamics and Kinetics of Drug Binding
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 164.00
BioNMR in Drug Research
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 198.00
Chirality in Drug Research
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 204.00
Antiviral Drug Strategies
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (EPUB Format)
CHF 159.00
Thermodynamics and Kinetics of Drug Binding
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 164.00
Protein Kinases as Drug Targets
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 156.00
Fragment-based Drug Discovery
Estimation of Solubility, Permeability, Absorption and Bioavailability
Estimation of Solubility, Permeability, Absorption and Bioavailability
Ebook (PDF Format)
CHF 164.00
Bewertungen
Anmelden