Advances in Metallodrugs

The book provides a recent update and achievements in the preparation and application of newly designed metal-based drugs. Over the past few decades, medicinal inorganic chemistry as an interdisciplinary sub-area of bioinorganic chemistry, has received a growing attention of researchers in the search for promising antimicrobial, antimalarial, antiviral, and antitumor chemotherapeutic agents. An excellent compilation of reports on metal complexes has revealed the potency of metal complexes as better therapeutic agents. Metal-containing drugs have several promising advantages over organic ligands and have gained the trust of researchers after the worldwide approval of the drug cisplatin. Their distinct mechanism of action makes them perfect candidates as alternatives to the conventional drugs to which resistance has already been shown. In this direction, a huge number of transition metal complexes have been synthesized and evaluated for their biological profiles. This book is organized into 12 important chapters that focus on the progress made by metal-based drugs as anticancer, antibacterial, antiviral, anti-inflammatory, and anti-neurodegenerative agents, as well as highlighting the application areas of newly discovered metallodrugs. This important and topical book: Discusses newly adopted methods involved in the design of effective metallodrugs Provides up-to-date developments in the application of metal-complex drugs Discusses the role of metallodrugs as promising chemotherapeutic agents Audience The book will be used extensively by researchers, engineers, and postgraduate students working in the fields of medical science, pharmacy, biotechnology and biomedical engineering.