Organic Azides

Organic azides are energy-rich and flexible intermediates for organic synthesis. They have found a variety of uses as reagents for the synthesis of heterocycles, as a masked amino function in natural compound synthesis, as the most important precursors of nitrenes, and as detonators, blowing agents for polymers, and functional groups in pharmaceuticals. In the past decade completely new perspectives have been developed for the use of azides in peptide chemistry, combinatorial chemistry, and heterocyclic synthesis. Organic azides have assumed an important position at the interfaces between chemistry, biology, medicine, and materials science. Organic Azides: Syntheses & Applications is an essential guide to the use and applications of this important class of compounds. Topics covered include the following aspects: synthesis and safety of azides the chemistry of vinyl azides small rings by azide chemistry rearrangement reactions of azides radical chemistry with azides cycloaddition reactions with azides click chemistry with azides dipolar cycloaddition reactions in peptide chemistry photochemistry of azides, and the azide/nitrene interface organometallic chemistry with azides applications in materials science, including azides in high energy materials, polymers and combinatorial chemistry applications in bioorganic chemistry, including azides in carbohydrate chemistry, natural products synthesis and Staudinger ligation Organic Azides: Syntheses & Application is a comprehensive, authoritative and up-to-date guide to these important reagents for organic chemists, drug discovery researchers, materials scientists and those interested in the chemistry of natural products.