Antibacterial Agents

Antibacterial Agents is an essential guide to an important class of chemotherapeutic drugs. In this full colour volume, compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. Topics are presented using an integrated lab-to-clinic approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects including links to current guidelines, significant drug interactions, cautions and contraindications, prodrugs and future improvements. This modern text summarises all the current knowledge on antibacterial drugs, and each chapter includes full colour diagrams and a set of key points for easy reference. Agents covered include: agents targeting DNA - quinolone, rifamycin, and nitroimidazole antibacterial agents agents targeting metabolic processes -  sulfonamide antibacterial agents and trimethoprim agents targeting protein synthesis - aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones agents targeting cell wall synthesis - ?-lactam and glycopeptide antibiotics, cycloserine, isoniazid, and daptomycin Antibacterial Agents will find a place on the bookshelves of students of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.