Kun (Hrsg.) Cheng

Advanced Delivery and Therapeutic Applications of RNAi

Ebook (EPUB Format)

RNA interference (RNAi) is a process in living cells whereby small double stranded RNA interferes with the expression of specific genes with complementary nucleotide sequence. Like many nucleic acid-based therapies, RNAi has great potential in treating various life-threatening diseases. However, the poor stability and cellular uptake of RNAi molecules remain considerable barriers to their efficient delivery which is paramount to a successful therapy. This book provides a comprehensive introduction to RNAi delivery, then goes on to discuss different delivery strategies, and concludes with current applications in various diseases. It covers: M… Mehr

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Produktdetails

Weitere Autoren: Mahato, Ram I. (Hrsg.)

ISBN: 978-1-118-61073-2
EAN: 9781118610732
Produktnummer: 16382398
Verlag: Wiley
Sprache: Englisch
Erscheinungsjahr: 2013
Seitenangabe: 536 S.
Plattform: EPUB
Masse: 7'008 KB
Auflage: 2. Aufl.

Über den Autor

Professor Kun Cheng, Division of Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, USAProfessor Cheng's research interests include the delivery and therapeutic applications of RNAi for breast cancer, prostate cancer, liver diseases, and type I diabetes. He has been working in the area of nucleic acids since 2002. He is co-editor of Advanced Drug Delivery with Dr. Ashim Mitra and Dr. Chi Lee (Wiley, 2012). He has also co-edited a themed issue entitled siRNA Delivery with Dr. Ram Mahato for the journal Molecular Pharmaceutics, and has developed and taught a graduate course entitled Protein and Nucleic Acid Drug Delivery. Professor Ram I. Mahato, Department of Pharmaceutical Sciences, School of Pharmacy, University of Tennessee Health Science Center, USAProfessor Mahato is a full professor of Pharmaceutics and Drug/Gene Delivery at the University of Tennessee Health Science Center Memphis. He is the author or co-author of 85 peer reviewed articles and book chapters. He has also edited/written five books and six special journal issues. He is a Special Features Editor of Pharmaceutical Research and on the editorial board of several journals. His research interest includes delivery and targeting of small molecules, oligonucleotides, siRNA and genes.