Prostate Biopsy Interpretation: An Illustrated Guide

Prostate needle biopsy specimens account for an important portion of a surgical pathologist's daily work. There is, however, a significant error rate when diagnosing prostate cancer in needle biopsies. Furthermore, the modified Gleason grading scheme is being only slowly adopted, and there is considerable variation in reporting. This book covers all the practical issues related to the interpretation of prostatic biopsies in day-to-day practice, including: biopsy sampling and processing; the diagnosis of limited cancer; differentiation of prostate cancers from benign lesions and recognition of histologic variants; the recognition and clinical significance of atypical diagnoses and HGPIN; the identification of recently described entities; the contemporary approach to Gleason grading; the utility of immunohistochemical markers and emerging molecular markers; and the reporting of prostate biopsies. The book contains numerous carefully selected, high-quality color images and uses algorithms, flow charts, and tables to simulate the thought and decision-making process upon encountering common clinical scenarios during sign-out of prostate biopsy. It will appeal especially to practicing surgical pathologists as well as to pathology residents and fellows in training who require a handy resource designed for use in daily practice.