Anti-Cancer N-Heterocyclic Carbene Complexes of Gold(III), Gold(I) and Platinum(II)
Thiol "Switch-on" Fluorescent Probes, Thioredoxin Reductase Inhibitors and Endoplasmic Reticulum Targeting Agents
This thesis focuses on the development of gold- and non-classical platinum-based anti-cancer agents that display distinctively different anti-cancer mechanisms compared to the commonly used cisplatin. These metal complexes contain N-heterocyclic carbene (NHC) ligands which are able to form strong M-C(NHC) bonds, conferring high stability and favorable lipophilicity, reactivity and binding specificity of metal complexes on biomolecules. The author demonstrates significant advances made in anti-cancer gold(III), gold(I) and platinum(II) complexes. Detailed chemical synthesis, in vitro and/or in vivo anti-cancer activities are clearly presented…
Mehr
CHF 150.00
Preise inkl. MwSt. und Versandkosten (Portofrei ab CHF 40.00)
V103:
Folgt in ca. 5 Arbeitstagen
Produktdetails
- ISBN: 978-981-10-9221-3
- EAN: 9789811092213
- Produktnummer: 27273781
- Verlag: Springer Singapore
- Sprache: Englisch
- Erscheinungsjahr: 2018
- Seitenangabe: 180 S.
- Masse: H23.5 cm x B15.5 cm x D0.9 cm 283 g
- Auflage: Softcover reprint of the original 1st ed. 2016
- Abbildungen: Paperback
- Gewicht: 283
2 weitere Werke von Taotao Zou:
Bewertungen
Anmelden