Transporters as Drug Carriers
Structure, Function, Substrates
Dieser Band aus der Reihe Methods and Principles in Medicinal Chemistry beleuchtet die Rolle molekularer Wirkstofftransporter im Kontext der Therapieoptimierung und der Aufklärung von Wirkstoffresistenzen. Alle bekannten Transporterklassen (vom Mikroorganismus bis zum Menschen) werden vorgestellt.
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Produktdetails
Weitere Autoren: Folkers, Gerd (Reihe Hrsg.) / Kubinyi, Hugo (Reihe Hrsg.) / Chiba, Peter (Hrsg.) / Ecker, Gerhard F. (Hrsg.)
- ISBN: 978-3-527-62743-1
- EAN: 9783527627431
- Produktnummer: 13855903
- Verlag: Wiley-Vch
- Sprache: Englisch
- Erscheinungsjahr: 2009
- Seitenangabe: 449 S.
- Plattform: PDF
- Masse: 6'578 KB
Über den Autor
Gerhard Ecker is the head of the Pharmacoinformatics Initiative at the Department of Medicinal Chemistry, University of Vienna. He studied Pharmacy at the University of Vienna (Ph.D. thesis advisors: W. Fleischhacker and C.R. Noe) and did post-doctoral work with J. Seydel in Borstel (Germany) where he started his SAR and QSAR studies on P-glycoprotein. His main scientific interests are pharmacoinformatic approaches to target drug efflux pumps, in silico screening methods for promiscuous targets, and non-linear methods in drug design. Peter Chiba is a senior scientist and lecturer at the Medical University of Vienna. He holds a doctorate in Medicine from the University of Vienna and worked at the Universities of Nijmegen (The Netherlands) and South Florida (USA) as a Fulbright scholar and post-doctoral associate. His research focuses on multidrug transport and resistance to drugs in treatment of cancer and microbial disease.
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