Evidence Synthesis for Decision Making in Healthcare
In the evaluation of healthcare, rigorous methods of quantitative assessment arenecessary to establish interventions that are both effective and cost-effective. Usually a single study will not fully address these issues and it is desirable to synthesize evidence from multiple sources. This book aims to provide a practical guide to evidence synthesis for the purpose of decision making, starting with a simple single parameter model, where all studies estimate the same quantity (pairwise meta-analysis) and progressing to more complex multi-parameter structures (including meta-regression, mixed treatment comparisons, Markov models of disease prog…
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Produktdetails
Weitere Autoren: Abrams, Keith R. / Sutton, Alexander J. / Welton, Nicky J. / Ades, A. E.
- ISBN: 978-1-118-30540-9
- EAN: 9781118305409
- Produktnummer: 13897976
- Verlag: Wiley
- Sprache: Englisch
- Erscheinungsjahr: 2012
- Seitenangabe: 320 S.
- Plattform: EPUB
- Masse: 9'126 KB
Über den Autor
Nicky Welton, Department of Social Medicine, University of BristolDr Welton's research includes Bayesian statistical modeling in epidemiology and evidence synthesis and evidence consistency. Alex Sutton, Department of Health Sciences, University of LeicesterDr Sutton, senior lecture in medical statistics, has a primary research interest in meta-analysis. This specifically includes methods to combine evidence from disparate sources, and methods to deal with the problem of publication bias. With numerous published papers in a variety of journals he has also collaborated on over 15 substantive evidence synthesis projects. He is lead author on one of the first textbooks on meta-analysis in medicine and is co-editor on a recently published Wiley book on publication bias. Nicola Cooper, Department of Health Sciences, University of LeicesterDr Cooper's primary research interest is in the interface and integration of medical statistics and health economics. This specifically includes methods for statistical modelling of cost data, integration of evidence synthesis within a decision-modelling context, handling of missing data in economic evaluations conducted alongside clinical trials, and the application of Bayesian statistical methods to all of the above. Keith Abrams, Department of Health Sciences, University of LeicesterProfessor Abrams' research interests include the development and application of Bayesian methods in healthcare evaluation, systematic reviews and meta-analysis, and the joint modeling of longitudinal and time-to-event data. He has published dozens of articles in numerous international journals and is the co-author of two Wiley books in this area. Anthony E Ades, Department of Social Medicine, University of Bristol with over 30 published articles in the last three years, Professor Ades' research interests include statistical methods for multi-parameter evidence synthesis in epidemiology, disease mapping and economic evaluation; Bayesian decision theory and the expected value of information; statistical and epidemiological methods in infectious disease surveillance.
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