Glycobiology and Medicine

The potential for glycobiology to improve the practice of medicine has been well recognised, which is why biannual meetings concerning the association have been taking place for the last 14 years. The science of glycobiology has matured rapidly, and with it the far reaching clinical implications are becoming understood. The next decade is going to see this final frontier of science conquered. The impact this understanding of glycobiology will have upon our practice of medicine is going to be exciting. The 7th Jenner Glycobiology and Medicine Symposium was designed to reflect these advances. All the major clinical areas were involved, with contributions from pivotal players in science and medicine. TOC:From the contents:Glycosylation: Disease Targets and Therapy.- Long Alkylchain Iminosugars Block the HCV P7 Ion Channel.- The Bovine Viral Diarrhoea Virus: A Model for the Study of Antiviral Molecules Interfering with N-Glycosylation and Folding of Envelope Glycoprotein.- Antibody Recognition of a Carbohydrate Epitope: A Template for HIV Vaccine Design.- Interaction of Schistosome Glycans with the Host Immune System.- The Mannan-Binding Lectin (MBL) of Complement Activation: Biochemistry, Biology and Clinical Implications.- Killer Cell Lectin-like Receptors and the Natural Killer Cell Gene Complex.- Glycosylation Influences the Ligand Binding Activities of Mannose Receptor.- Human Immunoglobulin Glycosylation and the Lectin Pathway of Complement Activation.- Gelatinase B Participates in Collagen II Degradation and Releases Glycosylated Remnant Epitopes in Rheumatoid Arthritis.- Hyaluronan in Immune Processes.- Glycosylation and the Function of the T Cell Co-receptor CD8.- Immunogenecity of Calreticulin-bound Murine Leukemia Virus Glycoprotein.- Glycosylation and GPI Anchorage of the Prion Protein.- Glycosylation Defects and Muscular Dystrophy.