Quasispecies: From Theory to Experimental Systems
This volume brings together recent developments in quasispecies theory extended to variable environments and practical applications in elucidating viral dynamics and treatment designs. In particular, the existence of an error threshold in rugged fitness landscapes has opened the way to a new antiviral strategy termed lethal mutagenesis, which is now under intensive theoretical, experimental and clinical investigation. As such the book explains how an understanding of quasispecies dynamics within infected organisms has increased our knowledge of viral disease events. From a clinical perspective, population dynamics highlights important problem…
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Produktdetails
Weitere Autoren: Schuster, Peter (Hrsg.)
- ISBN: 978-3-319-23897-5
- EAN: 9783319238975
- Produktnummer: 18746190
- Verlag: Springer International Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2016
- Seitenangabe: 372 S.
- Masse: H24.1 cm x B16.0 cm x D2.6 cm 723 g
- Auflage: 1st ed. 2016
- Abbildungen: HC runder Rücken kaschiert
- Gewicht: 723
Über den Autor
Esteban Domingo is a professor at the Spanish Research Council at Centro de Biología Molecular Severo Ochoa (Madrid) and President of the Spanish Society of Virology. He is a member of EMBO and Real Academía de Ciencias Exactas, Físicas y Naturales. Peter Schuster, em. professor of University of Vienna is a member of Leopoldina, Nationale Akademie der Wissenschaften, National Academy of Sciences USA, European Academy of Sciences and Arts and several other institutions. He worked together with Manfred Eigen and developed together with him the concepts of quasispecies and hypercycles.
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