Amino Acids, Peptides and Proteins in Organic Chemistry

Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international who's who in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures.Volume 1: Origins and Synthesis of Amino AcidsVolume 2: Modified Amino Acids, Organocatalysis and EnzymesVolume 3: Building Blocks, Catalysis and Coupling ChemistryVolume 4: Protection Reactions, Medicinal Chemistry, Combinatorial SynthesisVolume 5: Analysis and Function of Amino Acids and PeptidesThis third volume in the series presents an in depth account of recent developments in the (bio-)synthesis of amino acids and peptides. Divided into two parts, the first section deals with amino acids as building blocks, including the generation of alpha-amino acids, beta-lactams, and heterocycles. The second section is devoted to the synthesis of peptides, with the focus on solid phase synthesis. However, solution phase peptide synthesis is covered as well, as are topics such as coupling reagents, chemical ligation, peptide purfication and automation.