Derek J. (Hrsg.) Chadwick
Variation in the Human Genome
Ebook (PDF Format)
The mapping of human genes is proceeding rapidly, and genes associated with specific inherited diseases are being identified, often providing insight into the molecular cause of the disease. At the moment, however, little consideration is being given to the variation present in different human populations. This variation bears a record of the population history of our species and how this has been affected by diseases, ecological adaptations, and pharmacological and nutritional responses. Treatment of inherited diseases that involve several genes will require knowledge of the degree and nature of genetic variation present in a population. Thi…
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Beschreibung
The mapping of human genes is proceeding rapidly, and genes associated with specific inherited diseases are being identified, often providing insight into the molecular cause of the disease. At the moment, however, little consideration is being given to the variation present in different human populations. This variation bears a record of the population history of our species and how this has been affected by diseases, ecological adaptations, and pharmacological and nutritional responses. Treatment of inherited diseases that involve several genes will require knowledge of the degree and nature of genetic variation present in a population. This book discusses methods of analysing population genetic data and how contemporary genetic heterogeneity arises during the evolution and migration of human populations. Specific disorders ? such as cystic fibrosis, ?-thalassaemia, fragile X, phenylketonuria and tumour development susceptibility ? are used to illustrate this genetic variability and mechanisms of gene mutation and evolution.
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Produktdetails
Weitere Autoren: Cardew, Gail (Hrsg.)
- ISBN: 978-0-470-51489-4
- EAN: 9780470514894
- Produktnummer: 13965864
- Verlag: Wiley
- Sprache: Englisch
- Erscheinungsjahr: 2008
- Seitenangabe: 340 S.
- Plattform: PDF
- Masse: 18'466 KB
Über den Autor
Derek J. Chadwick and Gail Cardew are editors for Variation in the Human Genome and other scientific titles.
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