Theivendren Panneer Selvam
Thiazole - An Active Scaffold against Bacterial Strains
Novel Thiazole Derivatives
Buch
A series of Ethyl-3-methyl-5-(substituted-phenyl)-6,7,8,9-tetrahydro-5H-thiazolo[2,3-b]quinazoline-2-carboxylate derivatives have been synthesize from cyclohexanone and substituted benzaldehyde with the aim of developing potential antimicrobials and antitubercular agents. It was characterized by FT-IR, 1H NMR and Mass spectroscopy. All the newly synthesized compounds were screened for their antimicrobial and antifungal activities on Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus luteus, Bacillus cereus (Gram-positive bacteria), Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia (Gram-negative bacteria), Aspergillus…
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Beschreibung
A series of Ethyl-3-methyl-5-(substituted-phenyl)-6,7,8,9-tetrahydro-5H-thiazolo[2,3-b]quinazoline-2-carboxylate derivatives have been synthesize from cyclohexanone and substituted benzaldehyde with the aim of developing potential antimicrobials and antitubercular agents. It was characterized by FT-IR, 1H NMR and Mass spectroscopy. All the newly synthesized compounds were screened for their antimicrobial and antifungal activities on Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus luteus, Bacillus cereus (Gram-positive bacteria), Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia (Gram-negative bacteria), Aspergillus fumigates, Candida albicans (Fungi). All the synthesized compounds were also evaluated for their antitubercular activity against Mycobacterium tuberculosis strain H37Ra.
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Produktdetails
Weitere Autoren: James, Caiado Richa / Arumugam, Sivakumar
- ISBN: 978-3-659-32439-0
- EAN: 9783659324390
- Produktnummer: 37415366
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2013
- Seitenangabe: 200 S.
- Masse: H22.0 cm x B15.0 cm x D1.2 cm 316 g
- Abbildungen: Paperback
- Gewicht: 316
Über den Autor
Dr. Theivendren Panneer Selvam M.Pharm., Ph.D Assistant ProfessorPES's Rajaram and Tarabai Bandekar College of PharmacyFaramagudi, Ponda, Goa, INDIAProf.K.R.S.Sambasiva Rao, Ph.D., DSc. Acharya Nagarjuna University, Guntur, A.P., INDIA Prof.Bhaskara R. Jasti, Ph.D. ChairmanUniversity of Pacific, Stockton, CA
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