Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases
This volume focuses on the role of sphingosine-1-phosphate (S1P) and its analogs in the induced sequestration of lymphocytes in secondary lymphoid organs or in the microenvironment of tissues involved in infection or autoimmune disease. Initial chapters define the pathways to understand S1P signaling. They cover the organization of signaling systems, the structural biology of the S1P1 receptor, and the chemical and genetic tools that are available and useful to explore this area of research and therapeutics. The later chapters highlight S1P and endothelial integrity, lymphocyte migration in the spleen, and S1P agonist in controlling immunopa…
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Produktdetails
Weitere Autoren: Oldstone, Michael B. A. (Hrsg.)
- ISBN: 978-3-319-05878-8
- EAN: 9783319058788
- Produktnummer: 16279618
- Verlag: Springer International Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2014
- Seitenangabe: 192 S.
- Masse: H24.1 cm x B16.0 cm x D1.6 cm 459 g
- Auflage: 2014
- Abbildungen: HC runder Rücken kaschiert
- Gewicht: 459
Über den Autor
Michael B.A. Oldstone has been a successful series editor, volume editor and author of Current Topics in Microbiology and Immunology for several decades. He is a professor based at The Scripps Research Institute, La Jolla, CA, and a member of the National Academy of Sciences. Hugh Rosen is a professor at The Scripps Research Institute, La Jolla, CA, USA.
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