A. Douglas (Hrsg.) Kinghorn
Progress in the Chemistry of Organic Natural Products 115
Buch
This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the trop…
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Beschreibung
This book describes current understandings and recent progress into a varied group of natural products. In the first chapter the role that total synthesis may play in revising the structures proposed for decanolides, which are ten-membered lactones found primarily in fungi, frogs, and termites is presented. The following chapter presents the development of the intriguing plant-derived sesquiterpene lactone, thapsigargin, a potent inhibitor of the enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential as a lead compound to treat cancer. The third chapter covers the potential of various plant phenolic compounds for treating the tropical and sub-tropical infectious disease, leishmaniasis. In addition the volume presents recent advances related to the plant alkaloid, cryptolepine, which is of particular interest as a lead for the treatment of malaria, trypanosomiasis, and cancer.
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Produktdetails
Weitere Autoren: Falk, Heinz (Hrsg.) / Dirsch, Verena M. (Hrsg.) / Asakawa, Yoshinori (Hrsg.) / Liu, Ji-Kai (Hrsg.) / Gibbons, Simon (Hrsg.)
- ISBN: 978-3-030-64855-8
- EAN: 9783030648558
- Produktnummer: 38682394
- Verlag: Springer International Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2022
- Seitenangabe: 216 S.
- Masse: H23.5 cm x B15.5 cm x D1.1 cm 335 g
- Auflage: 1st ed. 2021
- Abbildungen: Paperback
- Reihenbandnummer: 115
- Gewicht: 335
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