Phylogenomics of vertebrate serpins
Molecular evolution of vertebrate Serine protease inhibitors
The serpins constitute a superfamily of proteins that fold into a conserved tertiary structure and employ a sophisticated, irreversible suicide-mechanism of inhibition. More than 6000 serpins have been identified, occurring in all three forms of the life - the eukaryotes, the prokaryotes and the archea. Vertebrate serpins can be conveniently classified into six groups (V1 - V6), based on three independent biological features - gene organization, diagnostic amino acid sites and rare indels. In the present work, the phylogenetic relationships of serpins from Nematostella vectensis, Strongylocentrotus purpuratus, Ciona intestinalis, and selected…
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Produktdetails
- ISBN: 978-3-659-33645-4
- EAN: 9783659336454
- Produktnummer: 37732736
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2013
- Seitenangabe: 280 S.
- Masse: H22.0 cm x B15.0 cm x D1.7 cm 435 g
- Abbildungen: Paperback
- Gewicht: 435
Über den Autor
Dr. Abhishek Kumar is a genomics researcher with foucs on applied bioinformatics at the CAU Kiel (Germany). Previously, he worked at the Uni-Padova (Italy) and Uni-Bielefeld (Germany), NCBS-TIFR and SBT-Madurai Kam. Uni.(India).He is interested in genomics, fungal genetics, transcriptomics, next-generation DNA sequencing and molecular evolution.
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