PHARMACOKINETICS AND BIOAVAILABILITY OF SILYMARIN
IN-VIVO KINETICS OF SILYMARIN (MILK THISTLE); A HEPATOPROTECTIVE AGENT
Silymarin is a purified extract from milk thistle (Silybum marianun (L.) Gaertn), composed of a mixture of isomeric flavonolignans: silybin (its main, active component), isosilybin, silydianin and silychristin. This extract has been empirically used as a remedy for almost 2000 years, and remains being used as a medicine for many types of acute and chronic liver diseases. Despite its routinely clinical use as hepatoprotectant, the mechanisms underlying its beneficial effects remain largely unknown. The purpose of this study was to investigate the pharmacokinetics and bioaequivalence of two brands of Silymarin tablets in healthy mal…
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Produktdetails
Weitere Autoren: Ahmad, Mahmood / Madni, Asadullah
- ISBN: 978-3-8443-0004-8
- EAN: 9783844300048
- Produktnummer: 37828285
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2011
- Seitenangabe: 136 S.
- Masse: H22.0 cm x B15.0 cm x D0.8 cm 221 g
- Abbildungen: Paperback
- Gewicht: 221
Über den Autor
Muhammad Usman, B.Pharm.,M.Phil(Pharmaceutics),is currently working as a Lecturer of Pharmaceutics in the Department of Pharmacy, The Islamia University of Bahawalpur,Punjab,Pakistan. The areas of special interest include Pharmacokinetics,Novel Drug Delivery systems and Bioanalytical method development and validation.
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