Oxidative Folding of Peptides and Proteins
The formation of disulfide bonds is probably the most influential modification of peptides and proteins. An elaborate set of cellular machinery exists to catalyze and guide this process. In recent years, significant developments have been made in both our understanding of the in vivo situation and the in vitro manipulation of disulfide bonds. This is the first monograph to provide a comprehensive overview of this exciting and rapidly developing area. It offers in-depth insights into the mechanisms of in vivo and in vitro oxidative folding of proteins as well as mono- and multiple-stranded peptides. Procedures applied for laboratory and indust…
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Produktdetails
Weitere Autoren: Alewood, Paul (Beitr.) / Freedman, R B (Beitr.) / Allemann, Rudolf K (Beitr.) / Barlos, Kleomenis (Beitr.) / Glockshuber, Rudolf (Beitr.) / Buchner, Johannes (Hrsg.) / Jakob, Ursula (Beitr.) / Neidle, Stephen (Reihe Hrsg.) / Feige, Matthias Johannes (Beitr.) / Gebendofer, Katharina (Beitr.) / Hell, K (Beitr.) / Holmgren, Arne (Beitr.) / Craik, David (Beitr.) / Rabenstein, Dallas L (Beitr.) / Winter, Jeannette (Beitr.) / Fass, D (Beitr.) / Wade, John D (Beitr.) / Bulaj, Grzegorz (Beitr.) / Bulleid, Neil (Beitr.) / Lange, C (Beitr.) / Haehnel, Wolfgang (Beitr.) / Hilvert, Donald (Beitr.) / Rudolph, R (Beitr.) / Adermann, Knut (Beitr.) / Neupert, Walter (Beitr.)
- ISBN: 978-1-84755-926-5
- EAN: 9781847559265
- Produktnummer: 36241683
- Verlag: Royal Society Of Chemistry
- Sprache: Englisch
- Erscheinungsjahr: 2008
- Seitenangabe: 448 S.
- Plattform: PDF
- Masse: 0 KB
Über den Autor
Johannes Buchner is based in the Department of Chemistry at the Technical University of Munich. His research interests focus on protein folding in vivo and in vitro, molecular chaperones, folding catalysts, antibody production and engineering. He is author and co-author of 150 publications including the Protein Folding Handbook. Luis Moroder is based at the Max Planck Institute. His research interests focus on biorganic chemistry, peptide chemistry, structure-function studies of bioactive peptides, conformational analysis and protein engineering. He is author and co-author of over 500 publications.
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