Non-Mendelian Genetics in Humans
When rediscovered at the turn of the century, Mendel's laws were found to be applicable to humans, but from the beginning they were fraught with problems. Sex-linked traits and linked genes defied Mendel's rules. Later, other exceptions were found, including sporadic cases, non-penetrance, variable expressivity, and preferential parental transmission.In this book, Harry Ostrer observes that some of these problems can be explained by incomplete ascertainment, typing errors and modifying genes. He then goes on to systematically explore the evidence for a number of newer genetic processes that were not foreseen by Mendel and his intellectual hei…
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Produktdetails
- ISBN: 978-0-19-506877-1
- EAN: 9780195068771
- Produktnummer: 22401991
- Verlag: OXFORD UNIV PR
- Sprache: Englisch
- Erscheinungsjahr: 1998
- Seitenangabe: 216 S.
- Masse: H24.1 cm x B16.4 cm x D1.8 cm 535 g
- Auflage: New
- Reihenbandnummer: 35
- Gewicht: 535
Über den Autor
Harry Ostrer, M.D., is Associate Professor of Pediatrics and Pathology and Director of the Human Genetics Program at New York University Medical Center. His current research is concentrated in the areas of genetic control of male sexual development, the genetic basis of cancer susceptibility, human population genetics, and assuring fairness in the use of genetic information.
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