Nanocarrier Systems for Drug Delivery for the Treatment of Asthma
Liposomes as Model Carrier Systems
This book presents work on nanocarrier systems for pulmonary drug delivery for use in the treatment of asthma. Using sucrose as a carrier, liposomes were generated or dispersed in situ from proliposomes within the medical nebulisers investigated. The Pari (air-jet) and the Omron (vibrating-mesh) nebulisers produced large mass and lipid outputs with a large lipid fraction deposited in the lower stage of a two-stage impinger. The Liberty (Ultrasonic) nebuliser failed to deliver more than 6% of the lipid employed.Multilamellar liposomes were generated from ethanol-based proliposomes. The resultant vesicles entrapped 62% of the available salbutam…
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Produktdetails
Weitere Autoren: Taylor, Kevin / Ahmed, Waqar
- ISBN: 978-3-8465-3261-4
- EAN: 9783846532614
- Produktnummer: 37799873
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2011
- Seitenangabe: 256 S.
- Masse: H22.0 cm x B15.0 cm x D1.5 cm 399 g
- Abbildungen: Paperback
- Gewicht: 399
Über den Autor
Dr A Elhissi & Prof W Ahmed (University of Central Lancashire) are involved the study of nanoparticles and nanomaterials in medical and engineering applications. Prof K Taylor (University of London) is researching liposomal systems for drug delivery involving formulation, manufacture and evaluation of their potential for controlled drug delivery.
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