Lin Wang
IGHD/BIK/EGFR/SPINK1/CCNA2-repressive mechanism in lung adenocarcinoma
Buch
Different Pearson mutual-positive-correlation IGHD/BIK/EGFR/SPINK1/CCNA2-repressive molecular network was constructed from the overlapping of GRNInfer and Pearson under IGHD/BIK/EGFR/SPINK1/CCNA2 CC =-0.25 in high lung adenocarcinoma compared with low human normal adjacent tissues, respectively. We propose IGHD inhibited DNA damage-induced inside-out cell differentiation through ENO1-SLC22A18-RECQL4-SQSTM1-PYCRL; BIK inhibiting axon guidance-induced membrane motility through BCC3-LGR4-DPY19L1-LIMK1; EGFR inhibited inflammatory immune-induced membrane development through CD180-TNFRSF17-POU2AF1; SPINK1 outside-inside-out inhibitive axon induced…
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Beschreibung
Different Pearson mutual-positive-correlation IGHD/BIK/EGFR/SPINK1/CCNA2-repressive molecular network was constructed from the overlapping of GRNInfer and Pearson under IGHD/BIK/EGFR/SPINK1/CCNA2 CC =-0.25 in high lung adenocarcinoma compared with low human normal adjacent tissues, respectively. We propose IGHD inhibited DNA damage-induced inside-out cell differentiation through ENO1-SLC22A18-RECQL4-SQSTM1-PYCRL; BIK inhibiting axon guidance-induced membrane motility through BCC3-LGR4-DPY19L1-LIMK1; EGFR inhibited inflammatory immune-induced membrane development through CD180-TNFRSF17-POU2AF1; SPINK1 outside-inside-out inhibitive axon induced apoptosis through BUB1B-CCNA2-NCAPG-HIST1H2BD; CCNA2 inhibiting hypoxia, T cell and endocrine-induced cytoplasm differentiation through DPP41-DPP43-SLC2A5-TMEM63A-ENC12 in high lung adenocarcinoma based on integrative GO, KEGG, GenMAPP, BioCarta and disease databases. They are very useful to develop a new route and identify novel markers and potential drugs for prognosis and therapy for studying the pathogenesis
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Produktdetails
Weitere Autoren: Huang, Juxiang / Jiang, Minghu
- ISBN: 978-3-659-67099-2
- EAN: 9783659670992
- Produktnummer: 37620971
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2014
- Seitenangabe: 108 S.
- Masse: H22.0 cm x B15.0 cm x D0.6 cm 179 g
- Abbildungen: Paperback
- Gewicht: 179
Über den Autor
Prof. Dr. Lin Wang has received her Ph.D in Klinik für Innere Medizin, Friedrich-Schiller-Universität Jena, Germany. Currently, she is working as Biomedical Center professor in Beijing University of Posts and Telecommunications (BUPT).
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