Hyaluronidase, a potential target for the management of snakebite
Hyaluronidase, a spreading factor
The venom hyaluronidases are non-toxic and popularly known as 'spreading factors' as they facilitates the spreading of target specific toxins from the bitten site to the general circulation by degrading hyaluronic acid present in extracellular matrix of basement membrane surrounding the blood capillaries. Neutralization of venom hyaluronidases not only protect the tissues at bitten site but also increases the survival time of a victim/pray by limiting the easy diffusion of target specific toxins. Therefore, hyaluronidase inhibition is considered as rate limiting step in the better management of snakebite. It could be an effective therapeutic…
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Produktdetails
Weitere Autoren: K., Kemparaju (Hrsg.)
- ISBN: 978-3-659-37808-9
- EAN: 9783659378089
- Produktnummer: 37415459
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2013
- Seitenangabe: 168 S.
- Masse: H22.0 cm x B15.0 cm x D1.0 cm 268 g
- Abbildungen: Paperback
- Gewicht: 268
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