Gene Delivery Systems

Gene therapy is a technique that modifies a person's genes to treat or cure disease and can be used as an alternative to using drugs or surgery. Here the authors discuss the development of gene therapy today, from the technology involved to gene correction and the advances in genome editing. Several new drug delivery systems are explored for the applications of gene therapy. These are found to be useful in treating chronic illnesses, including cancer and infectious diseases.Key Features:Overview of the development of gene therapyProvides the most up to date information on the development of gene therapy, from the technology involved to gene correction and genome editingPresents CRISPR gene therapy recent trends and applicationsDiscusses siRNA, mRNA, and DNA plasmidsA collection of 15 chapters containing recent research, this volume covers the development of gene therapy, the technology involved, clinical applications of siRNA, non-viral vector-based mRNA delivery using nanotechnology, and RNA based vaccines for treating the infectious diseases. It also presents the current application of CRISPR/Cas9 gene-editing technique, an approach that has recently been given the Nobel Prize in Chemistry, 2020.