Formulation And Evaluation of Metformin and Glimepiride
Sustained Release Metformin And Immidiate Release Glimepiride
The objective of this research was to develop a combined anti-diabetic formulation of two different drugs acting by different mechanism. So they can complement each other and together lower the blood glucose level effectively. Metformin and glimepiride act by different mechanisms. Glimepiride reduce hyper glycaemia by enhancing insulin secretion, whereas metformin acts to improve insulin sensitivity and suppress hepatic glucose output. Because of their complementary mechanism of action, combination therapy with glimepiride and metformin would be rational and may lead to benefits in terms of improved glycaemic control and improved tolerability…
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Produktdetails
Weitere Autoren: Gupta, Khushboo
- ISBN: 978-3-659-78131-5
- EAN: 9783659781315
- Produktnummer: 37536301
- Verlag: LAP Lambert Academic Publishing
- Sprache: Englisch
- Erscheinungsjahr: 2017
- Seitenangabe: 84 S.
- Masse: H22.0 cm x B15.0 cm x D0.5 cm 143 g
- Abbildungen: Paperback
- Gewicht: 143
Über den Autor
Anil Kumar Sahdev*( Assistant Professor) and Khushboo Gupta (M.Pharma), Innovative college of pharmacy Greater noida (Uttar Pradesh), India.
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